Devices and methods for facilitating controlled bone growth...

A - Human Necessities – 61 – F

Patent

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A61F 2/44 (2006.01)

Patent

CA 2561938

Bone implantable devices and methodologies permit careful application of biologically active substances and management of bone growth processes. The device includes a body (300) defining a carrier receiving area for locating adjacent bone. Carrier material (310) is located in the carrier receiving area. Substance is delivered onto carrier material through a port (308). A pathway (370) delivers substance from the carrier receiving area to the bone surface. The body may be in the form of a spinal fusion cage, facet fusion screw, artificial joint, bone fixation plate, interbody graft, IM nail, hip stem, or other bone-to-bone appliances or bone-to-device appliances. In use, carrier is installed in the carrier receiving area of the device. The device is then implanted adjacent a bone. The substance is applied to the carrier for subsequent delivery to the bone. By doping carrier material after device implantation, inadvertent contact of the substance with non-target bone is more easily eliminated.

Cette invention concerne des dispositifs implantables et des méthodes permettant l'application précise de substances biologiquement actives et la gestion de processus de croissance osseuse. Le dispositif comprend un corps (300) définissant une région portante pour la mise en place d'un os adjacent. Le matériau porteur (310) se trouve dans la zone portante correspondante. Une substance est administrée sur la surface portante via un orifice (308). Un canal (370) permet de faire passer cette substance de la surface portante sur la surface de l'os. Le corps peut se présenter sous forme de cage de fusion vertébrale, de vis de fusion de facettes, d'articulation artificielle, de plaque de fixation osseuse, de greffe inter-élément, de clou centro-medullaire, de tige pour hanche, et autres accessoires de liaison os-os ou os-dispositif. Le dispositif est ensuite implanté contre un os. La substance est appliquée sur la surface en direction de l'os. Le dopage du matériau porteur après implantation du dispositif permet d'éliminer plus facilement un contact accidentel de cette substance avec un os non concerné.

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