Devices and methods for high-pressure refolding of proteins

B - Operations – Transporting – 01 – L

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B01L 1/00 (2006.01)

Patent

CA 2630802

Disclosed are devices for holding samples, particularly liquid samples, during high-pressure treatment. The devices enable a variety of functions, such as high-throughput screening of samples in multi-compartment device embodiments, and adjustment of solution conditions during high-pressure treatment. The devices are designed to maintain integrity during the high-pressure conditions, and are optionally substantially impermeable to oxygen.

L~invention concerne des dispositifs destinés au support d~échantillons, notamment d~échantillons liquides, lors d~un traitement sous pression élevée. Ces dispositifs permettent diverses utilisations, telles que le criblage à haut débit d~échantillons dans des modes de réalisation multicompartiments du dispositif et l~ajustement des conditions de solutions lors d~un traitement sous pression élevée. Ces dispositifs sont conçus pour maintenir l~intégrité des échantillons dans des conditions de pression élevée et peuvent éventuellement être sensiblement imperméables à l~oxygène.

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