Devices and methods to image objects by time delay integration

Details Devices and methods to image objects by time delay integration Devices and methods to image objects by time delay integration

G - Physics

01

N

G01N 1/30 (2006.01)

Patent

CA 2535301

Devices and methods for automated collection and image analysis are disclosed that enable identification or classification of microscopic objects aligned or deposited on surfaces. Such objects, e.g. detectably labeled rare target cells, are magnetically or non-magnetically immobilized and subjected to Time Delay Integration imaging (TDI). Incorporation of TDI technology into image cytometry analysis, like CellTracks®, makes it possible to image moving objects with very high sensitivity and signal-to-noise ratios. Implementation of TDI camera technology with dual excitation and multispectral imaging of enriched rare cells provides a rapid system for detection, enumeration, differentiation and characterization of imaged rare cells on the basis of size, morphology and immunophenotype.

La présente invention concerne des dispositifs et des procédés de recueil automatisé et d'analyse d'image qui permettent d'identifier ou de classifier des objets microscopiques alignés ou déposés sur des surfaces. Ces objets, par exemple des cellules cible rares marquées de façon détectable, sont immobilisés de manière magnétique ou non et soumis à une imagerie par intégration dans le temps (TDI). L'incorporation de la technologie TDI dans l'analyse cytométrique d'image, telle que la technologie CellTracks?®¿, rend possible l'imagerie d'objets mobiles avec une grande sensibilité et des rapports signal sur bruit élevés. La mise en oeuvre de la technologie de caméra TDI avec une excitation duale et une imagerie multispectrale de cellules rares enrichies fournit un système rapide de détection, de numération, de différenciation et de caractérisation de cellules rares imagées fondé sur la taille, la morphologie et sur l'immunophénotype.

Affiliated with

Also associated with

Rating

Devices and methods to image objects by time delay integration does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Devices and methods to image objects by time delay integration, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Devices and methods to image objects by time delay integration will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1345136