Devices for conducting binding assays

G - Physics – 01 – N

Patent

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Details

G01N 33/543 (2006.01) B01L 3/00 (2006.01) B01L 3/14 (2006.01) G01N 33/52 (2006.01)

Patent

CA 2432698

An apparatus for use in an assay to be conducted upon a fluid sample suspected of containing an analyte of interest, comprises a vessel (10) for receiving a sample, and an element (1) for capturing an analyte of interest, said element being insertable into said vessel for the purposes of the assay, and being coated on at least one surface (3) with a specific binding partner for said analyte of interest, and said element further having on a surface (4) remote from said coated surface means (5) adapted for manipulating the element for convenient analysis, whereby it is possible to detect and quantify microorganisms, particularly assay for infective agents such as bacteria, and viral particles and prions, or other particles that may be associated with a disease state, especially in humans.

Appareil destiné à un dosage appliqué à un échantillon liquide qui pourrait contenir un analyte d'intérêt; il comprend un récipient (10) accueillant un échantillon et un élément (1) pour capturer un analyte d'intérêt. Cet élément peut être inséré dans ledit récipient pour effectuer un dosage, et au moins une des ses surfaces (3) est revêtue d'un partenaire de liaison spécifique à cet analyte d'intérêt. Ledit élément comporte aussi une surface (4) éloignée de ladite surface à revêtement et conçue pour manipuler plus facilement l'élément pendant l'analyse, ce qui permet de détecter et de quantifier les micro-organismes et notamment d'effectuer des dosages d'agents infectieux tels que bactéries, particules virales et prions ou d'autres particules pouvant être associées à un état pathologique, plus particulièrement chez les humains.

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