Devices for in-vivo determination of the compliance function...

A - Human Necessities – 61 – B

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A61B 5/021 (2006.01) A61B 5/026 (2006.01) A61B 5/029 (2006.01) G06F 17/00 (2006.01) A61B 5/028 (2006.01)

Patent

CA 2266883

A device for individual in-vivo determination of the compliance function C(p) = dV/dp of the vascular system downstream of a ventricle and/or systemic blood flow of a living being from the blood pressure p(t) and a reference cardiac output COref. The device comprises a) a pressure sensor which continuously determines the pressure p(t) in the aorta or in the vicinity of the aorta; b) a computer which b1) calculates the mean blood pressure MAP from the blood pressure p(t), b2) calculates the systemic resistance R of the body as Image CVP being an arbitrary central venous pressure which is ascertained or estimated, and COref being a reference value for the cardiac output, b3) takes at least the first differential of the blood pressure with respect to time p(t) = dp/dt, and b4) calculates the compliance function C(p) at least from p(t), p(t) and R using a nonlinear model.

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