Devices for performing ion-capture binding assays

Details Devices for performing ion-capture binding assays Devices for performing ion-capture binding assays

G - Physics

01

N

G01N 33/558 (2006.01) G01N 33/538 (2006.01) G01N 33/543 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2110049

This invention presents novel assay devices employing a capture reagent, involving a specific binding member attached to a charged substance, and a porous material containing a capture or reaction zone that is oppositely charged with respell to the capture reagent. In one embodiment, a test sample suspected of containing the analyze of interest is contacted with the capture reagent to form a charged capture reagent/analyte complex. The complex is then contacted to the oppositely charged capture or reaction zone to attract, attach, and immobilize the capture reagent/analyte complex. With an appropriate indicator reagent, both sandwich and competitive assays can be performed.

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