C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 311/80 (2006.01) A61K 31/352 (2006.01) A61K 31/496 (2006.01) A61K 31/5377 (2006.01) C07D 405/06 (2006.01) C07D 417/06 (2006.01)
Patent
CA 2183466
Pharmaceutical compositions are describecd for preventing neurotoxicity, comprising as active ingredient the sterospecific (+) enantiomer, having (3S, 4S) configuration of .DELTA.6 tetrahydrocannabinol type compounds. The composition are particularly effective in alleviating and even preventing neurotoxicity due to acute injuries to the central nervous system, including, mechanical trauma, compromised or reduced blood supply as may occur in cardiac arrest or stroke, or poisonings. They are also effective in the treatment of certain chronic degenerative diseases characterized by gradual neuronal loss.
On décrit des compositions pharmaceutiques destinées à la prévention de la neurotoxicité, comprenant, comme principe actif, l'énantiomère stéréospécifique (+) présentant la configuration (3S, 4S) des composés de type .DELTA.6 tétrahydrocannabinol. Ces compositions permettent d'atténuer et même prévenir de manière efficace la neurotoxicité induite par des blessures aiguës au niveau du système nerveux central, dont les traumatismes mécaniques, un apport sanguin déficient ou réduit tel que dans le cas d'un arrêt cardiaque, d'une attaque ou d'empoisonnements. Les compositions de l'invention permettent de traiter de manière efficace certaines affections dégénératives chroniques qui sont caractérisées par une dépopulation neuronale progressive.
Biegon Anat
Kloog Yoel
Mechoulam Raphael
Pop Emil
Sokolovsky Mordechai
Gowling Lafleur Henderson Llp
Pharmos Corporation
Ramot University Authority For Applied Research And Industrial D
Yissum Research Development Company Of The Hebrew University In
LandOfFree
Dexanabinol derivatives and their use as neuroprotective... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Dexanabinol derivatives and their use as neuroprotective..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Dexanabinol derivatives and their use as neuroprotective... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1838748