C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/805 (2006.01) A61K 47/48 (2006.01) C08B 37/00 (2006.01) C08B 37/02 (2006.01)
Patent
CA 2422908
An hemoglobin (Hb) - Dextran (Dx) conjugate having a molecular weight between 50 kD and 500 kD provides a blood substitute that results in acceptable erythrocyte sedimentation rate (ESR) and excretion rate (EXC) values. DxHb conjugates of the invention can be used for a variety of purposes as an alternative to blood.
Un conjugué d'hémoglobine (Hb) dextrane (Dx) ayant un poids moléculaire compris entre 50 kD et 500 kD constitue un substitut du sang qui produit des valeurs acceptables de vitesse de sédimentation des érythrocytes (VS) et de vitesse d'excrétion (VE). Les conjugués DxHb selon l'invention peuvent être utilisés dans diverses applications en tant que produit de remplacement du sang.
Tsai Sheung Pun
Wong Jeffrey Tze-Fei
Blake Cassels & Graydon Llp
Dextro-Sang Corporation
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