Dextran hexonic acid derivative, ferric hydroxide complex...

C - Chemistry – Metallurgy – 08 – B

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260/210, 260/222

C08B 37/02 (2006.01)

Patent

CA 1265790

- 12 - TITLE DEXTRAN HEXONIC ACID DERIVATIVE, FERRIC HYDROXIDE COMPLEX AND METHOD AND MANUFACTURE THEREOF APPLICANT POLYDEX PHARMACEUTICALS LTD. INVENTOR Anthony L. TOSONI Natu PATEL Kenneth COELHO ABSTRACT A hexonic acid derivative of dextran and a complex thereof with ferric hydroxide is used as an intermediate in the manufacture of an iron complex. The iron complex is used as an anti-anemia drug, primarily in animals and is stable and non-toxic it has a high iron content are obtained under carefully controlled conditions by reacting dextran having a molecular weight range between 2000 and 6000 with sodium chlorite; and then reacting with ferric hydroxide to produce the desired complex.

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