Dextrochlorpheniramine tannate

Details Dextrochlorpheniramine tannate Dextrochlorpheniramine tannate

C - Chemistry, Metallurgy

07

D

C07D 213/38 (2006.01) A61K 31/4402 (2006.01)

Patent

CA 2412463

The invention pertains to a novel composition comprising dextrochlorpheniramine tannate and to a method for preparing such tannate by reacting dextrochlorpheniramine free base at a temperature of about 60 to about 150°C with tannic acid preferably neat or as an aqueous slurry containing about 5 to about 30 wt.% water. The dextrochlorpheniramine tannate has extended release properties and is useful in pharmaceutical compositions as an antihistamine for human beings.

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