Dfmo and celecoxib in combination for cancer chemoprevention...

Details Dfmo and celecoxib in combination for cancer chemoprevention... Dfmo and celecoxib in combination for cancer chemoprevention...

A - Human Necessities

61

K

A61K 31/415 (2006.01) A61K 31/198 (2006.01) A61K 45/06 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2373931

Celecoxib, a COX-2 specific non-steroidal anti-inflammatory agent, is provided in combination with DFMO for the prevention and/or treatment of cancers. Provided with the present invention are pharmaceutically acceptable compositions that include a non-steroidal anti-inflammatory agent, celecoxib, together with an effective amount of difluoromethylornithine.

L'invention concerne l'utilisation combinée de célécoxib, un anti-inflammatoire COX-2 spécifique non stéroïde, et d'eflornithine hydrochloride pour la prévention et/ou le traitement du cancer. L'invention concerne en outre des compositions pharmaceutiquement acceptables renfermant l'anti-inflammatoire considéré et une quantité efficace d'eflornithine hydrochloride.

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