Dgks as modifiers of the p53 pathway and methods of use

Details Dgks as modifiers of the p53 pathway and methods of use Dgks as modifiers of the p53 pathway and methods of use

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) A61K 39/395 (2006.01) A61K 45/00 (2006.01) C12Q 1/00 (2006.01) C12Q 1/42 (2006.01) C12Q 1/48 (2006.01) C12Q 1/527 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01) G01N 33/573 (2006.01) G01N 33/574 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2449275

Human DGK genes are identified as modulators of the p53 pathway, and thus are therapeutic targets for disorders associated with defective p53 function.Methods for identifying modulators of p53,comprising screening for agents that modulate the activity of DKG are provided.

L'invention concerne les gènes DGK humains qui ont été identifiés comme étant des modulateurs du mécanisme d'action de p53, et qui constituent de ce fait des cibles thérapeutiques pour les troubles associés à une fonction p53 défectueuse. L'invention concerne également des procédés permettant d'identifier des modulateurs de p53 au moyen d'un criblage visant à rechercher des agents modulant l'activité de DKG.

Affiliated with

Also associated with

Rating

Dgks as modifiers of the p53 pathway and methods of use does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Dgks as modifiers of the p53 pathway and methods of use, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Dgks as modifiers of the p53 pathway and methods of use will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1544153