(di)-16-phenoxy-and 16-substituted phenoxy- 9-keto...

C - Chemistry – Metallurgy – 07 – C

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260/235.03

C07C 405/00 (2006.01)

Patent

CA 1149802

PA-909 - EPO Abstract of the Disclosure Novel 16-phenoxy and 16-(o, m or p)-substituted phenoxy derivatives of (dl)-9-keto-11.alpha.,15.alpha.-dihydroxy- 17,18,19,20-tetranorprosta-4,5,13-trans-trienoic acid, the pharmaceutically acceptable, non-toxic lower alkyl esters and salts thereof and processes for the production of such compounds. These compounds possess prostaglandin-like activities and thus are useful in the treatment of mammals where prostaglandins are indicated. They are particularly useful as inhibitors of gastric acid secretion; and as agents for the control of asthmatic attack, because of their bronchodilating activity.

331348

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