Di- and trivalent small molecule selectin inhibitors

Details Di- and trivalent small molecule selectin inhibitors Di- and trivalent small molecule selectin inhibitors

C - Chemistry, Metallurgy

07

H

C07H 15/203 (2006.01) A61K 31/70 (2006.01) A61P 37/02 (2006.01) C07H 15/18 (2006.01) C07H 15/26 (2006.01)

Patent

CA 2221991

The present invention provides compounds having structure (II), and the pharmaceutically acceptable salts, esters, amides and prodrugs thereof for inhibiting the binding of E-selectin, P-selectin or L-selectin to sialyl-Lewis x or sialyl- Lewis a by using the compounds.

La présente invention se rapporte à des composés de la structure (II), ainsi qu'à leurs sels, esters, amides et promédicaments pharmaceutiquement acceptables.

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