Di-fluoro containing compounds as cysteine protease inhibitors

Details Di-fluoro containing compounds as cysteine protease inhibitors Di-fluoro containing compounds as cysteine protease inhibitors

C - Chemistry, Metallurgy

07

C

C07C 255/46 (2006.01) A61K 31/275 (2006.01) A61P 9/10 (2006.01) A61P 19/02 (2006.01)

Patent

CA 2664878

The present invention is directed to compounds that are inhibitors of cysteine proteases, in particular, cathepsins B, K, L, F, and S, and are therefore useful in treating diseases mediated by these proteases. The present invention is directed to pharmaceutical compositions comprising these compounds and processes for preparing them.

La présente invention concerne des composés qui sont des inhibiteurs des cystéine-protéases, en particulier des inhibiteurs des cathepsines B, K, L, F et S, et qui sont donc utilisables pour traiter des maladies induites par ces protéases. La présente invention concerne des compositions pharmaceutiques comprenant ces composés et leurs procédés de préparation.

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