Di(nitroxyalkyl)amides of pyridine-2,4- and...

Details Di(nitroxyalkyl)amides of pyridine-2,4- and... Di(nitroxyalkyl)amides of pyridine-2,4- and...

C - Chemistry, Metallurgy

07

D

167/229, 260/296

C07D 213/81 (2006.01) A61K 31/44 (2006.01) C07D 213/82 (2006.01)

Patent

CA 2034206

- 1 - HOE 90/F 010 ABSTRACT OF THE DISCLOSURE: The invention relates to di(nitroxyalkyl)amides of pyridine-2,4- and -2,5-dicarboxylic acids, of the formula I Image (I) in which R has the indicated meanings. The compounds according to the invention inhibit the enzymes proline hydroxylase and lysine hydroxylase and can accordingly be employed as fibrosuppressants and immunosuppressants.

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