Di-substituted 1,2-dioxetane compounds having increased...

Details Di-substituted 1,2-dioxetane compounds having increased... Di-substituted 1,2-dioxetane compounds having increased...

C - Chemistry, Metallurgy

07

F

C07F 9/655 (2006.01) C07C 69/734 (2006.01) C07F 9/12 (2006.01) C09K 11/07 (2006.01) G01N 33/52 (2006.01) C07D 321/00 (2006.01)

Patent

CA 2182325

Stable, enzymatically triggered chemiluminescent 1,2- dioxetanes with improved water solubility are provided. Dioxetanes further substituted with two or more water-solubilizing groups disposed on the dioxetane structure provide superior performance by eliminating the problem of reagent carryover when used in assays performed on capsule chemistry analytical systems. Compositions comprising a dioxetane with two or more water-solubilizing groups, a non-polymeric cationic surfactant enhancer and optionally a fluorescer, for providing enhanced chemiluminescence are also provided.

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