Di-substituted 1,4-piperidine esters and amides having 5-ht4...

C - Chemistry – Metallurgy – 07 – D

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C07D 401/14 (2006.01) A61K 31/445 (2006.01) C07D 211/26 (2006.01) C07D 401/12 (2006.01)

Patent

CA 2209904

Pharmacologically active novel esters and amides of di-substituted 1,4- piperidine as 5-HT4 antagonists of general formula (I), wherein A, X, Y and R have the meanings specified in the description, processes for their preparation and pharmaceutical compositions containing them, are disclosed.

Nouveaux esters et amides pharmaceutiquement actifs de 1,4-pipéridine disubstituée en tant qu'antagonistes de 5-HT4, de formule générale (I) dans laquelle A, X, Y et R sont tels que spécifiés dans la description, procédés de préparation desdits esters et amides et compositions les contenant.

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