Di-t-butylphenyl alkyl and benzyl ethers

C - Chemistry – Metallurgy – 07 – C

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167/233, 167/262

C07C 59/68 (2006.01) C07C 65/24 (2006.01) C07D 257/04 (2006.01) C07D 257/06 (2006.01)

Patent

CA 1325430

ABSTRACT OF THE DISCLOSURE: Disclosed are novel compounds of the formula: Image wherein A is phenylene or an alkylene group containing two to about seven carbon atoms; and B is carboxyl, tetrazolyl or carboxamidetetrazolyl; or a derivative of a compound wherein B is carboxyl selected from the group consisting of lower alkyl ester, a (lower)alkylamino(lower)alkyl ester, a pharmaceutically acceptable (lower)alkylamino(lower)alkyl ester acid-addition salt and a pharmaceutically acceptable carboxylate salt; or a derivative of a compound wherein B is tetrazolyl or carboxamidotetrazolyl selected from a pharmaceutically acceptable alkali metal or alkaline earth salt of the tetrazolyl moiety. These novel compounds are useful as antiallergic agents. Synthetic intermediates for making such compounds are also disclosed.

564299

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