Diacylderivatives of glycerylphosphorylcholine having...

Details Diacylderivatives of glycerylphosphorylcholine having... Diacylderivatives of glycerylphosphorylcholine having...

C - Chemistry, Metallurgy

07

F

167/231, 260/430

C07F 9/10 (2006.01) A61K 31/685 (2006.01) C07F 9/09 (2006.01) C07F 9/58 (2006.01)

Patent

CA 1300152

-1- "Diacylderivatives of glycerylphosphorylcholine having therapeutical ac- tivity, a process for their preparation and related pharmaceutical compo- sitions" ABSTRACT The diacylesters, particularly bis(pyridyl-3-carboxilate) of glyceryl- phosphorylcholine, both optically active L(alpha) or racemic D,L(alpha) and their complexes having general formula: Image wherein: Y represents Image or Image M represents Ca, Mg, Al, Zn X represents a halogen, particularly chlorine, n=2,3 ed m= 0,1 are anti-dislipemic and cerebroactive agents. Their preparation takes place through acylation with an anhydride of a complex of glycerylphosphorylcholine with calcium or zinc chloride.

496835

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