Diagnosing and treating viral infections associated with...

Details Diagnosing and treating viral infections associated with... Diagnosing and treating viral infections associated with...

C - Chemistry, Metallurgy

12

Q

167/202, 150/8.5

C12Q 1/70 (2006.01) A61K 31/70 (2006.01) C07H 21/00 (2006.01)

Patent

CA 1336685

Virus infections promoting Chronic Fatigue can be diagnosed by assessing the 2'-5'A/ RNase L pathway, including measurement of 2'-5'A oligonucleotide levels in the patient's circulating peripheral leucocytes, and comparing these resuls with those of healthy individuals. Double-stranded RNAs, notably mismatched dsRNAs, when administered in appropriate amounts, increase the 2'-5'A and normalize the antiviral pathway in patients with Chronic Fatigue Syndrome and improve the clinical symptoms.

604511

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