Diagnosis and treatment of atherosclerosis and coronary...

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G01N 33/564 (2006.01) A61K 39/00 (2006.01) A61P 9/00 (2006.01) C07K 14/47 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2373285

The present invention concerns novel uses for human HSP60 in methods of treatment or diagnosis of the human body, more particularly diagnostic test methods, the manufacture of diagnostic tests, and diagnostic test kits for patients with vascular disorders due to atherosclerosis, having a tendency to heat shock protein-induced complement activation, for example to myocardial disorders such as coronary heart disease.

La présente invention concerne des nouvelles utilisations de la protéine HSP60 humaine dans des méthodes thérapeutiques ou diagnostiques du corps humain, et plus particulièrement des méthodes de tests diagnostiques, l'élaboration de tests diagnostiques et des équipements de tests diagnostiques destinés à des patients atteints de troubles vasculaires dus à l'athérosclérose et présentant une prédisposition à une activation du complément déclenchée par une protéine de choc thermique, cette activation entraînant notamment des troubles du myocarde tels que les coronaropathies.

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