C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/54 (2006.01) C07K 16/40 (2006.01) C12N 9/12 (2006.01) A61K 48/00 (2006.01) C12Q 1/48 (2006.01) C12Q 1/68 (2006.01) G01N 33/573 (2006.01)
Patent
CA 2239692
The present invention relates to AUR-1 and/or AUR-2 polypeptides, nucleic acids encoding such polypeptides, cells, tissues and animals containing such nucleic acids, antibodies to such polypeptides, assays utilizing such polypeptides, and methods relating to all of the foregoing. Methods for treatment, diagnosis, and screening are provided for AUR-1 and/or AUR-2 related diseases or conditions characterized by an abnormal interaction between an AUR-1 and/or AUR- 2,polypeptide and an AUR-1 and/or AUR-2 binding partner.
L'invention porte sur les polypeptides AUR-1 et/ou AUR-2, les acides nucléiques codant pour eux, les cellules, tissus et animaux renfermant lesdits acides nucléiques, les anticorps de ces polypeptides, et des méthodes leur étant associées. Elle porte également sur des méthodes de diagnostic, de dépistage et de traitement de troubles liés aux AUR-1 et/ou AUR-2 et à des états caractérisés par des interactions anormales entre les polypeptides AUR-1 et/ou AUR-2 et leurs partenaires de fixation.
Mossie Kevin G.
Plowman Gregory D.
Smart & Biggar
Sugen Inc.
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