C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/54 (2006.01) A61K 38/45 (2006.01) C12N 5/10 (2006.01) C12N 9/12 (2006.01) C12Q 1/48 (2006.01) C12Q 1/68 (2006.01) G01N 33/573 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2318352
The present invention relates to AUR1 and/or AUR2 polypeptides, nucleic acids encoding such polypeptides, cells, tissues and animals containing such nucleic acids, antibodies to such polypeptides, assays utilizing such polypeptides, and methods relating to all of the foregoing. Methods for treatment, diagnosis, and screening are provided for AUR1 and/or AUR2 related diseases or conditions characterized by an abnormal interaction between an AUR1 and/or AUR2 polypeptide and an AUR1 and/or AUR2 binding partner.
L'invention concerne des polypeptides d'AUR1 et/ou AUR2, des acides nucléiques codant ces polypeptides, des cellules, des tissus et des animaux contenant ces acides nucléiques, des anticorps contre ces polypeptides, des méthodes de dosage mettant en application ces polypeptides, ainsi que des procédés pouvant être appliqués à l'énoncé ci-dessus. Elle concerne des procédés de traitement, de diagnostic et de criblage de maladies associées à AUR1 et/ou AUR2 ou d'états caractérisés par une interaction anormale entre un polypeptide d'AUR1 et/ou AUR2 et un partenaire de liaison d'AUR1 et/ou AUR2.
Bischoff James R.
Mossie Kevin
Plowman Gregory D.
Smart & Biggar
Sugen Inc.
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