Diagnosis and treatment of gluten-induced autoimmune diseases

Details Diagnosis and treatment of gluten-induced autoimmune diseases Diagnosis and treatment of gluten-induced autoimmune diseases

G - Physics

01

N

G01N 33/573 (2006.01) C07K 16/40 (2006.01)

Patent

CA 2757598

The invention relates to selective diagnosis of gluten-induced autoimmune diseases by binding assays utilizing the main celiac epitope present on proteins of the transglutaminase family. The invention also relates to treatment of gluten-induced autoimmune diseases by inhibiting binding of celiac autoantibodies by therapeutic compounds.

Cette invention concerne le diagnostic sélectif des maladies auto-immunes induites par le gluten par des dosages de liaison au moyen de l'épitope cliaque principal présent sur les protéines de la famille des transglutaminases. Cette invention concerne également le traitement des maladies auto-immunes induites par le gluten par inhibition de la liaison d'auto-anticorps cliaques par des composés thérapeutiques.

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