C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 9/04 (2006.01) A61K 31/7088 (2006.01) A61K 38/44 (2006.01) A61K 39/00 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) A61P 35/00 (2006.01) C07K 16/40 (2006.01) C12N 5/12 (2006.01) C12N 9/02 (2006.01) G01N 33/53 (2006.01) G01N 33/574 (2006.01) G01N 33/58 (2006.01)
Patent
CA 2447367
The invention features a method for diagnosing and inhibiting growth of a malignant neoplasm in a mammal by contacting a cell or a bodily fluid of the mammal with an antibody which binds to an human aspartyl (asparaginyl) beta- hydroxylase (HAAH) polypeptide. Methods of immunization to generate an HAAH- specific immune response are also within the invention.
L'invention concerne un procédé destiné à réaliser un diagnostic et à inhiber la croissance d'une tumeur maligne chez un mammifère, consistant à mettre en contact une cellule ou un fluide corporel du mammifère et un anticorps qui se lie à un polypeptide humain aspartyl (asparaginyl) bêta-hydroxylase (HAAH). Elle concerne aussi des procédés d'immunisation destinés à produire un réponse immunospécifique au polypeptide HAAH.
de La Monte Suzanne
Deutch Alan H.
Ghanbari Hossein A.
Wands Jack R.
Mbm Intellectual Property Law Llp
Panacea Pharmaceuticals Inc.
Rhode Island Hospital
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