Diagnosis and treatment of multiple sulfatase deficiency and...

Details Diagnosis and treatment of multiple sulfatase deficiency and... Diagnosis and treatment of multiple sulfatase deficiency and...

C - Chemistry, Metallurgy

12

N

C12N 15/53 (2006.01) A61K 31/7088 (2006.01) A61K 38/36 (2006.01) A61K 38/44 (2006.01) A61K 38/46 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) A61P 3/00 (2006.01) C07K 16/40 (2006.01) C12N 5/10 (2006.01) C12N 9/02 (2006.01) C12N 15/52 (2006.01) C12N 15/63 (2006.01) C12Q 1/26 (2006.01) C12Q 1/68 (2006.01) C40B 40/08 (2006.01) C40B 40/10 (2006.01) G01N 33/573 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2515708

This invention relates to methods and compositions for the diagnosis and treatment of Multiple Sulfatase Deficiency (MSD) as well as other sulfatase deficiencies. More specifically, the invention relates to isolated molecules that modulate post-translational modifications on sulfatases. Such modifications are essential for proper sulfatase function.

L'invention concerne des procédés et des compositions pour le diagnostic et le traitement du déficit multiple en sulfatases (DMS) ainsi que d'autres déficits en sulfatases. Plus spécifiquement, l'invention concerne des molécules isolées qui modulent des modifications post-traduction sur des sulfatases. Des telles modifications sont essentielles pour une juste fonction des sulfatases.

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