Diagnosis of and therapy for hereditary haemorrhagic...

C - Chemistry – Metallurgy – 12 – N

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C12N 15/18 (2006.01) A01K 67/027 (2006.01) A61K 38/18 (2006.01) A61K 48/00 (2006.01) C07H 21/00 (2006.01) C07K 14/71 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2205964

A method of diagnosing hereditary haemorrhagic telangiectasia (HHT) which includes the steps of: obtaining a sample of genomic DNA from a patient or fetus; and determining whether the DNA contains a mutation in a gene encoding endoglin, betaglycan, TGF-.beta. type I receptor (RI), TGF-.beta. type II receptor (RII), or TGF-.beta./activin type I receptor (TSR-I), such a mutation being an indication that the patient or fetus bears a gene making the patient or fetus susceptible to HHT.

La présente invention concerne un procédé de diagnostic de l'angiomatose hémorragique familiale ou "HHT". Ce procédé consiste d'abord à prélever un échantillon d'ADN génomique sur un patient ou un foetus. Le procédé consiste ensuite à déterminer si l'ADN contient une mutation dans un gène codant pour l'endogline, pour le bétaglycan, pour le récepteur Type I (RI) du TGF-.beta. (facteur de croissance transformant .beta.) ou pour le récepteur Type II (RII) du TGF-.beta. ou de l'activine. En effet, une telle mutation est signe que le patient ou le foetus est porteur d'un gène qui fait de lui un sujet risquant de développer une HHT.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Diagnosis of and therapy for hereditary haemorrhagic... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Diagnosis of and therapy for hereditary haemorrhagic..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Diagnosis of and therapy for hereditary haemorrhagic... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1889701

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.