G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/50 (2006.01)
Patent
CA 2587647
The invention features methods and compositions for diagnosis, including prognosis, of conditions associated with decreased arginine bioavailability (which can result from dysregulated arginine metabolism, e.g., due to increased arginase activity) by assessing in a sample from a subject the ratio of arginine to one or more, usually two or more, modulators of arginine bioavailability. In one embodiment, the ratio of arginine to (ornithine + citrulline) is assessed to aid in diagnosis.
L'invention porte sur des procédés et des compositions qui permettent d'établir le diagnostic, et le pronostic, d'états associés à une biodisponibilité réduite de l'arginine (pouvant être entraînée par une dérégulation du métabolisme de l'arginine, due par exemple à une activité augmentée de l'arginine) en évaluant, dans un prélèvement effectué chez un sujet, le rapport entre l'arginine et au moins un, en général au moins deux modulateurs de la biodisponibilité de l'arginine. Dans un mode de réalisation, on évalue le rapport entre l'arginine et (l'ornithine + la citrulline) afin de faciliter le diagnostic.
Hazen Stanley L.
Morris Claudia R.
Children's Hospital & Research Center At Oakland
Fetherstonhaugh & Co.
The Cleveland Clinic Foundation
LandOfFree
Diagnosis of conditions associated with decreased arginine... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Diagnosis of conditions associated with decreased arginine..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Diagnosis of conditions associated with decreased arginine... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1886673