A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 48/00 (2006.01)
Patent
CA 2587790
Mouse proteins differentially expressed in serum, in comparisons of normal vs. hyperinsulinemic, hyperinsulinemic vs. type 2 diabetic, and normal vs. type 2 diabetic white adipose tissue have been identified, as have corresponding human proteins. The human molecules, or antagonists thereof, may be used for protection against hyperinsulinemia or type 2 diabetes, or their sequalae.
Selon l'invention, on a identifié des protéines de souris exprimées différemment dans le sérum, lors de la comparaison entre normal et hyperinsulinémique, hyperinsulinémique et diabétique de type II, et normal et diabétique de type II, avec des tissus adipeux, ainsi que des protéines humaines correspondantes. Les molécules humaines ou des antagonistes de celles-ci peuvent être utilisés pour la protection contre l'hyperinsulinémie ou le diabète de type II, ou leurs conséquences.
Kopchick John J.
Okada Shigeru
Sankaran Sudha
Kopchick John J.
Ohio University
Okada Shigeru
Sankaran Sudha
Smart & Biggar
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