Diagnosis of hyperinsulinemia and type ii diabetes and...

Details Diagnosis of hyperinsulinemia and type ii diabetes and... Diagnosis of hyperinsulinemia and type ii diabetes and...

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) A61K 38/17 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2557181

Mouse genes differentially expressed in comparisons of normal vs. hyperinsulinemic, hyperinsulinemic vs. type 2 diabetic, and normal vs. type 2 diabetic muscle by gene chip analysis have been identified, as have corresponding human genes and proteins. The human molecules, or antagonists thereof, may be used for protection against or diagnosis hyperinsulinemia or type 2 diabetes, or their sequelae.

L'invention concerne l'identification de gènes murins exprimés de façon différentielle dans la comparaison d'un muscle de patient normal à un muscle de patient souffrant d'hyperinsulinémie, d'un muscle de patient souffrant d'hyperinsulinémie à un muscle de patient souffrant de diabète de type 2, et d'un muscle de patient normal à un muscle de patient souffrant de diabète de type 2 par analyse à puce à ADN, ainsi que les gènes humains et protéines humaines correspondants. Les molécules humaines, ou les antagonistes de celles-ci, peuvent être utilisés dans la protection contre l'hyperinsulinémie ou le diabète de type 2, ou leurs séquelles.

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