Diagnosis of trichomonas vaginitis by detecting formate in...

Details Diagnosis of trichomonas vaginitis by detecting formate in... Diagnosis of trichomonas vaginitis by detecting formate in...

C - Chemistry, Metallurgy

12

Q

C12Q 1/32 (2006.01) G01N 33/569 (2006.01)

Patent

CA 2089186

ABSTRACT OF THE DISCLOSURE A method for the presumptive detection of Trichomonas in vaginal fluid, thereby providing an aid to the diagnosis of Trichomonas-caused vaginitis. A sample of vaginal fluid is combined with a test composition comprising an indicator system that provides a chromogenic response in the presence of formate; the detection of an elevated level of formate indicating the presumptive presence of Trichomonas. The test composition preferably comprises the enzyme formate dehydrogenase, NAD, an electron transfer agent, and a chromogenic indicator. MS-1689

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