Diagnosis, treatment, and prevention of vascular disorders...

G - Physics – 01 – N

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G01N 33/564 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2617637

Methods of detecting individuals at risk for atherosclerosis and related vascular diseases involving the detection of IL-l.alpha. autoantibodies, as well as therapeutic methods to prevent or treat atherosclerosis and related vascular disease by administering a pharmaceutical composition comprising IL- l.alpha. autoantibodies.

L'invention concerne des méthodes destinées à identifier des individus présentant un risque de développer une athérosclérose et des maladies vasculaires associées, et consistant à détecter des auto-anticorps dirigés contre l'IL-1.alpha., ainsi que des méthodes thérapeutiques destinées à prévenir ou traiter l'athérosclérose et une maladie vasculaire associée par administration d'une composition pharmaceutique comprenant des auto-anticorps dirigés contre l'IL-1.alpha..

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