Diagnostic agent for angiopathic diseases

A - Human Necessities – 61 – K

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A61K 51/10 (2006.01)

Patent

CA 2246666

A diagnostic agent for angiopathic diseases containing a monoclonal antibody against human smooth muscle myosin labeled with radioactive isotopes or active fragments of the antibody; a kit thereof; and a method of diagnostic imaging for angiopathic diseases by using the same. The invention permits the diagnostic imaging of angiopathic diseases such as dissecting aortic aneurysm and angiitis and the specification of the region affected by these diseases.

Cette invention concerne un agent d'aide au diagnostic des angiopathies qui contient un anticorps monoclonal dirigé contre la myosine des muscles lisses humains et marqué avec des isotopes radioactifs, ou des fragments actifs de cet anticorps. L'invention concerne une trousse contenant l'agent d'aide au diagnostic ainsi qu'un procédé d'imagerie diagnostique permettant le diagnostic d'angiopathies à l'aide de ladite trousse. L'invention permet d'obtenir une imagerie diagnostique d'angiopathies telles que l'anévrisme disséquant de l'aorte et l'angéite, ainsi que la spécification de la région affectée par ces maladies.

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