Diagnostic analytical method and kit

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/04 (2006.01)

Patent

CA 2395938

The invention provides a method for analysing for bacteria in a liquid sample comprising the following steps: a) contacting said sample with a substrate capable of retaining bacteria or bacterial fragments; b) staining any bacteria retained on said substrate with at least one solution comprising a first dye, said staining being conducted at a pH at which the dye has an overall positive charge and the bacteria has an overall negative charge; and c) inspecting the substrate for the presence of a stain whereby to indicate the presence of bacteria in said sample; with the proviso that where said liquid sample is other than a milk sample and substrate is a filter then said filter comprises a polysulfone or a derivative of a polysulfone.

L'invention concerne une méthode permettant d'analyser des bactéries dans un échantillon liquide, consistant à a) mette ledit échantillon en contact avec un substrat capable de retenir des bactéries ou des fragments de celles-ci; b) à colorer toute bactérie retenue sur ledit substrat à l'aide d'au moins une solution comprenant un premier colorant, la coloration étant effectuée à un pH auquel le colorant possède une charge globale positive, et les bactéries une charge globale négative; et c) à rechercher la présence d'une coloration sur le substrat, ce qui indique la présence de bactéries dans l'échantillon; à condition que ledit échantillon liquide soit autre qu'un échantillon de lait, et que le substrat soit un filtre renfermant un polysulfone ou un dérivé de polysulfone.

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