Diagnostic and diagnosis method for central nervous...

A - Human Necessities – 61 – K

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A61K 51/04 (2006.01) A61K 49/00 (2006.01) A61K 51/12 (2006.01) G01N 33/58 (2006.01) G01N 33/60 (2006.01)

Patent

CA 2201620

There is provided a diagnostic for central nervous abnormality, comprising a labeled transmitter substance of central nervous system or a labeled precursor of the transmitter substance, whose at least one of carbon atoms is substituted for a carbon isotope wherein the diagnostic is useful for diagnosing a central nervous abnormality (e.g. depression, Alzheimer's disease, schizophrenia, etc.) by applying it to a living body by oral administration of injection and examining a change in an amount of the carbon isotope in a breath of the living body.

La présente invention décrit un agent diagnostique pour anomalie nerveuse centrale, comprenant une substance de transmission marquée du système nerveux central ou un précurseur marqué de la substance de transmission, dont au moins un des atomes de carbone est remplacé par un isotope du carbone, dans lequel l'agent diagnostique est utile pour diagnostiquer une anomalie nerveuse centrale (par ex. dépression, maladie d'Alzheimer, schizophrénie, etc.) en l'appliquant à un corps vivant par voie orale ou injection et en examinant une modification de la quantité de l'isotope du carbone dans l'haleine du corps vivant.

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