Diagnostic and therapeutic agents

Details Diagnostic and therapeutic agents Diagnostic and therapeutic agents

C - Chemistry, Metallurgy

07

K

C07K 7/06 (2006.01) A61K 38/07 (2006.01) A61K 38/08 (2006.01) C07K 5/10 (2006.01)

Patent

CA 2605931

The present invention relates to tumor targeting units comprising a peptide sequence X-R-Y-P-Zn, or a pharmaceutically or physiologically acceptable salt thereof. The invention further relates to tumor targeting agents comprising at least one targeting unit according to the present invention, directly or indirectly coupled to at least one effector unit. The present invention further relates to diagnostic or pharmaceutical compositions comprising at least one targeting unit or at least one targeting agent according to the present invention, and to the use of targeting units or targeting agents according to the present invention for the preparation of a medicament for the treatment of cancer or cancer related diseases, especially for the treatment of non- small cell lung cancer or its metastases.

La présente invention concerne des unités de ciblage tumoral comprenant une séquence peptidique X-R-Y-P-Zn, ou un sel pharmaceutiquement ou physiologiquement acceptable de celles-ci. L'invention concerne en outre des agents de ciblage tumoral comprenant au moins une unité de ciblage selon la présente invention, directement ou indirectement couplée à au moins une unité effectrice. Elle concerne en plus des compositions diagnostiques ou pharmaceutiques comprenant au moins une unité de ciblage ou au moins un agent de ciblage selon la présente invention et l'utilisation d'unités de ciblage ou d'agents de ciblage selon la présente invention dans la préparation d'un médicament pour le traitement d'un cancer ou de maladies liées à un cancer, notamment pour le traitement d'un cancer bronchique non à petites cellules ou de ses métastases.

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