A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/395 (2006.01) A61K 31/7088 (2006.01) A61K 31/711 (2006.01) A61K 38/17 (2006.01) A61K 38/46 (2006.01) A61P 19/02 (2006.01) A61P 29/00 (2006.01) A61P 43/00 (2006.01) C07K 16/32 (2006.01) G01N 33/53 (2006.01) G01N 33/564 (2006.01) A61K 48/00 (2006.01)
Patent
CA 2404919
Participation of c-erbB-2 in the proliferation of synovial cells in patients with rheumatoid arthritis is clarified and the activation, expression, etc. of c-erbB-2 are inhibited. Thus, drugs usable as remedies for rheumatoid arthritis by inhibiting the proliferation of synovial cells mediated by c-erbB- 2 are provided.
La participation de c-erbB-2 dans la prolifération des cellules synoviales chez des patients souffrant de polyarthrite rhumatoïde a été mise en évidence et l'activation et l'expression notamment de c-erbB-2 sont par conséquent inhibées. Des médicaments utilisables contre la polyarthrite rhumatoïde par inhibition de la prolifération des cellules synoviales induites par c-erbB-2 sont ainsi proposés.
Homma Yoshimi
Sato Koichiro
Goudreau Gage Dubuc
Kyowa Hakko Kogyo Co. Ltd.
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