Diagnostic and therapeutic means for pathologies associated...

Details Diagnostic and therapeutic means for pathologies associated... Diagnostic and therapeutic means for pathologies associated...

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) G01N 33/50 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2505748

A nucleic acid is described that comprises at least one segment of the gene encoding a functional segment of the alpha 2 subunit of the Na,K pump (ATPase, ATP1A2) for use in the diagnosis or treatment of pathologies associated with migraine or with alternating hemiplegia of the childhood. Appropriate diagnostic kits and methods to identify agonist or antagonist agents are also described.

L'invention concerne un acide nucléique comprenant au moins un segment du gène codant un segment fonctionnel de la sous-unité alpha 2 de la pompe Na-K (ATPase, ATP1A2) que l'on utilise dans le diagnostic ou le traitement de pathologies associées à la migraine ou à l'hémiplégie alternante de l'enfant. Font également l'objet de cette invention des kits de diagnostic appropriés et des procédés d'identification d'agents agonistes ou antagonistes.

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