Diagnostic and therapeutic methods based on the l1 adhesion...

Details Diagnostic and therapeutic methods based on the l1 adhesion... Diagnostic and therapeutic methods based on the l1 adhesion...

A - Human Necessities

61

K

A61K 39/395 (2006.01) A61P 35/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/543 (2006.01) G01N 33/564 (2006.01) G01N 33/566 (2006.01) G01N 33/574 (2006.01) G01N 33/58 (2006.01) G01N 33/68 (2006.01) C07K 16/30 (2006.01)

Patent

CA 2415364

A method is described for the diagnosis of an ovarian or endometrial tumor or for a prognosis, characterized in that the L1 level is determined in a patient sample, preferably via an anti L1 antibody, the presence of L1 being an indication of the presence of an ovarian or endometrial tumor or a predisposition for such a tumor. Furthermore, methods for treating of ovarian or endometrial tumors are provided.

L'invention concerne une méthode de diagnostic ou de pronostic d'une tumeur de l'ovaire ou de l'endomètre, qui se caractérise en ce que le niveau L1 est déterminé dans un prélèvement effectué chez un patient, de préférence par le biais d'un anticorps anti-L1, la présence de L1 étant une indication de la présence d'une tumeur de l'ovaire ou de l'endomètre ou d'une prédisposition à une telle tumeur. L'invention concerne en outre des méthodes de traitement d'une tumeur de l'ovaire ou de l'endomètre.

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