A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/22 (2006.01) A61K 39/395 (2006.01) C07K 16/26 (2006.01) G01N 33/53 (2006.01) G01N 33/74 (2006.01)
Patent
CA 2257140
Compositions comprising OB-R agonists and methods of treatment for conditions such as systemic inflammatory response syndrome are provided. One suitable OB- R agonist ligand is recombinant human OB protein, also known as leptin. Also provided are methods and compositions for the treatment of obesity and OB resistance. Assay methods and kits relating to these conditions are also included.
L'invention concerne des compositions à base d'agonistes pour récepteurs OB (OB-R) et des procédés de traitement pour certains états comme le syndrome de réaction inflammatoire générale. La protéine humaine OB recombinée, également appelée leptine, est un ligand agoniste approprié pour OB-R. On décrit aussi des procédés et des compositions pour le traitement de l'obésité et la résistance propre aux OB, ainsi que des épreuves et des nécessaires à essai pour les états considérés.
Chen Sizhong
Feng Lili
Xia Yiyang
Fetherstonhaugh & Co.
The Scripps Research Institute
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