Diagnostic assay for trypanosoma cruzi infection

C - Chemistry – Metallurgy – 40 – B

Patent

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Details

C40B 40/10 (2006.01) C40B 30/04 (2006.01) G01N 33/543 (2006.01) C07K 14/44 (2006.01) C07K 17/00 (2006.01)

Patent

CA 2700000

A sensitive, multicomponent diagnostic test for infection with T. cruzi, the causative agent of Chagas disease, including methods of making and methods of use. Also provided is a method for screening T. cruzi polypeptides to identify antigenic polypeptides for inclusion as components of the diagnostic test, as well as compositions containing antigenic T. cruzi polypeptides.

La présente invention a pour objet un test de diagnostic sensible à composants multiples d'une infection à T. cruzi, l'agent responsable de la maladie de Chagas, y compris des procédés de fabrication et des procédés d'utilisation. L'invention a également pour objet un procédé de criblage de polypeptides de T. cruzi pour identifier des polypeptides antigéniques pour une inclusion en tant que composants du test de diagnostic, ainsi que des compositions contenant des polypeptides antigéniques de T. cruzi.

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