Diagnostic assay for trypanosoma cruzi infection

G - Physics – 01 – N

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G01N 33/569 (2006.01) A61K 39/005 (2006.01) C07K 14/44 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2563796

A sensitive, multicomponent diagnostic test for infection with T. cruzi, the causative agent of Chagas disease, including methods of making and methods of use. Also provided is a method for screening T. cruzi polypeptides to identify antigenic polypeptides for inclusion as components of the diagnostic test, as well as compositions containing antigenic T. cruzi polypeptides.

La présente invention concerne un test de diagnostic sensible à composants multiples destiné à l'infection par le T. cruzi, l'agent responsable de la maladie de Chagas. L'invention concerne également des méthodes et des procédés permettant de mettre au point et d'utiliser un tel test de diagnostic. En outre, cette invention concerne une méthode permettant de cribler les polypeptides T. cruzi pour identifier les polypeptides antigéniques afin de les introduire en tant que composants du test de diagnostic, ainsi que des compositions contenant les polypeptides T. cruzi antigéniques.

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