C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01)
Patent
CA 2705195
Methods are disclosed for the identification of gene sets that are differentially expressed in PBMCs of patients diagnosed with a pre-diabetic disease state and overt type II diabetes, 3 gene and 10 gene signatures are shown to accurately predict a diabetic disease state in a patient. The application also described kits for the rapid diagnosis of diabetic disease states in patients at a point of care facility.
La présente invention concerne des procédés pour l'identification d'ensembles de gènes qui sont exprimés de manière différentielle dans des cellules mononuclées du sang périphérique (PBMC) de patients diagnostiqués comme étant dans un état pré-diabétique et de diabète de type 2 manifeste : on a noté que 3 et 10 signatures génétiques fournissent une prédiction précise d'un état diabétique chez un patient. L'invention concerne également des trousses pour le diagnostic rapide d'états diabétiques au niveau d'un point de service de soins.
Backus John W.
Derecho Carlo
Lee Dong U.
Palma John F.
Vener Tatiana
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Veridex Llc
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