Diagnostic device and its use

C - Chemistry – Metallurgy – 12 – Q

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150/9, 150/3.2

C12Q 1/32 (2006.01) C12Q 1/26 (2006.01)

Patent

CA 1211692

Abstract A diagnostic device for the detection of an increased concentration of dehydrogenases and/or oxid- ases in the fluids of humans, animals or plants, which consists of a carrier which bonds a redox dyestuff, and a substance mixture, adjusted to a pH value in the acid range, of the substrate corresponding to the particular dehydrogenase, a hydrogen donor compound and at least one redox dyestuff is described. The device has the peculiarity that the carrier contains polar groups and the substance mixture for detecting exclusively patho- logically increased concentrations of the particular dehydrogenase and/or oxidase is adjusted to a pH value of below 5Ø The device is suitable for diagnos- ing malignant growths in very different organs, for example in the female genital area.

435085

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