Diagnostic marker for interferon responsiveness in multiple...

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/68 (2006.01) A61K 38/21 (2006.01) C12P 19/34 (2006.01) C12Q 1/00 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2580299

Disclosed is a method of determining interferon responsiveness in a patient suffering from multiple sclerosis. The method comprises determining an amount of a XAF-1 gene expression level in a blood sample, which is obtained from the patient undergoing interferon therapy. The amount of the XAF-1 gene expression level in the blood sample is then correlated with the responsiveness of the patient to the interferon.

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