Diagnostic method for glaucoma

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/68 (2006.01)

Patent

CA 2475690

The present invention relates to an ex vivo method for the diagnosis and/or prediction of glaucoma. Said method comprises detecting in a tissue and/or blood sample of a human individual an altered gene expression pattern of at least genes selected from the group of genes related to tissue remodeling. Furthermore, the invention relates to a DNA microarray comprising nucleic acid probes of genes of the specified gene group.

L'invention concerne un procédé ex vivo servant à diagnostiquer et/ou à pronostiquer le glaucome. Ce procédé consiste à détecter dans un spécimen humain tissulaire et/ou sanguin une modification de la configuration de l'expression d'au moins des gènes sélectionnés dans le groupe de gènes associés à un remodelage tissulaire. Elle concerne, de plus, un microgroupe d'ADN composé de sondes d'acide nucléique de gènes du groupe indiqué.

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