Diagnostic method for transmissible spongiform encephalopathies

Details Diagnostic method for transmissible spongiform encephalopathies Diagnostic method for transmissible spongiform encephalopathies

G - Physics

01

N

G01N 33/68 (2006.01)

Patent

CA 2459500

Transmissible spongiform encephalopathy (TSE) is diagnosed in a subject by using mass spectrometry to observe a polypeptide in a sample of body fluid taken from the subject. The polypeptide is differentially contained in the body fluid of TSE-infected subjects and non-infected subjects, and has a molecular weight in the range of from 3500 to 30000.

L'invention concerne une encéphalopathie spongiforme transmissible (TSE) diagnostiquée chez un sujet au moyen d'une spectrométrie de masse pour observer un polypeptide dans un échantillon de fluide corporel prélevé sur le sujet. Le polypeptide est différentiellement contenu dans le fluide corporel de sujets contaminés par la TSE et de sujets non contaminés, et présente un poids moléculaire situé dans une plage comprise entre 3500 et 30000.

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