Diagnostic method of cirrhosis and hepatic cancer

Details Diagnostic method of cirrhosis and hepatic cancer Diagnostic method of cirrhosis and hepatic cancer

C - Chemistry, Metallurgy

12

Q

150/11, 150/15.5

C12Q 1/48 (2006.01)

Patent

CA 1335071

This invention relates to a method of diagnosing can- cerous diseases, which comprises measuring the amount of UDP-N-acetylglucosamine:glycoprotein N-acetylglucosaminyl- transferase in body fluid and evaluating the increase in its amount for the diagnosis of hepatic diseases. AFP, CEA and ?-glutamyltranspeptidase have hitherto been used as tumor markers for the diagnosis of hepatic cancer. But these conventional tumor markers show a pos- itivity rate of about 60 %, making early diagnosis almost impossible. The method of this invention employs UDP-N-acetyl- glucosamine:glycoprotein N-acetylglucosaminyltransferase as tumor marker, whereby early diagnosis of hepatic cancer can be made almost completely.

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