Diagnostic methods and gene therapy using reagents derived...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01) A61K 31/70 (2006.01) A61K 48/00 (2006.01) C07H 21/00 (2006.01) C07K 14/705 (2006.01) C07K 16/30 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2219221

The isolation and characterization of a metastasis tumor suppressor gene KAI1 is disclosed and diagnostic methods and gene therapy approaches utilizing reagents derived from the nucleotide and deduced amino acid sequences of the KAI1 gene are provided.

L'invention concerne l'isolation et la caractérisation d'un gène suppresseur de métastases KAI1, ainsi que des procédés de diagnostic et une thérapie génique faisant appel à des réactifs dérivés du nucléotide et de séquences d'acides aminés déduites du gène KAI1.

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